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Neff Functional Medicine Clinic<br />

🔬 Functional Medicine Testing for Burnout Recovery

Why Testing Matters in Burnout

When you’re in a state of burnout, your body isn’t just “tired”—it’s out of balance on multiple levels. Hormones, neurotransmitters, digestion, detox pathways, even your genes—everything is affected.

That’s why we don’t guess. We test.

At Neff Functional Medicine Clinic, we use cutting-edge diagnostic tools to uncover the root causes of chronic stress and exhaustion. Here’s how we do it:

🧫 GI360™ Stool Test

alcohol, red wine

Your Gut: The Front Line of Stress Resilience

Stress doesn’t just affect your mind—it reshapes your gut microbiome. The GI360™ provides a detailed map of your intestinal health.

🔍 What it measures:

  • Healthy vs. pathogenic bacteria

  • Parasites, yeast, and viruses

  • Inflammation and gut permeability

  • Digestive enzyme function

  • Short-chain fatty acid (SCFA) production like butyrate and acetate

đź’ˇ Why it matters for burnout:
Chronic stress increases intestinal permeability (“leaky gut”) and decreases beneficial microbes, which can lead to inflammation, nutrient malabsorption, and worsened mental health. Restoring gut balance is often the first step to restoring energy and mood.

Image by gĂĽnter from Pixabay

🧪 Organic Acids Test (OAT)

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Metabolism, Mitochondria & Mood Chemistry in One Simple Urine Test

The OAT is one of the most comprehensive functional lab tests we use for burnout. It gives a snapshot of over 70 metabolic markers from a single urine sample.

🔍 What it measures:

  • Mitochondrial energy production

  • Neurotransmitter metabolites (dopamine, serotonin, GABA)

  • Oxidative stress and detox burden

  • B-vitamin and antioxidant status

  • Candida and fungal markers

đź’ˇ Why it matters for burnout:
Burnout often involves mitochondrial fatigue—your cells can’t make enough energy. OAT reveals how well your body is fueling itself and breaking down stress hormones. It’s a vital tool to personalise supplementation and lifestyle interventions.

Image by gĂĽnter from Pixabay

🧬 DNA Life Genomic Testing

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Your Blueprint for Stress Resilience and Recovery

Your genes can influence how you metabolise stress, detoxify toxins, and use key nutrients.

🔍 What it analyses:

  • COMT, MAO, and MTHFR variants (affecting dopamine, serotonin, and methylation)

  • Detox pathways (like GST and CYP450 enzymes)

  • Inflammatory genes (e.g., TNF, IL-6)

  • Nutrient transport and receptor genes

đź’ˇ Why it matters for burnout:
Some people are genetically predisposed to slower detoxification, higher anxiety, or reduced antioxidant capacity. Knowing your genetic blueprint allows us to customise your recovery plan so it works with your biology—not against it.

Image by gĂĽnter from Pixabay

🦋 Thyroid Panel (TSH, Free T3, Free T4, rT3, Antibodies)

alcohol, red wine

Your Thyroid: The Metabolic Master Controller

The thyroid controls your energy, temperature regulation, weight, and cognitive function—all of which are deeply affected by stress.

🔍 What we test:

  • Thyroid Stimulating Hormone (TSH)

  • Free T3 and Free T4 (active thyroid hormones)

  • Reverse T3 (a stress-blocked form of thyroid hormone)

  • Thyroid antibodies (to screen for autoimmunity)

đź’ˇ Why it matters for burnout:
Stress can suppress thyroid function and drive autoimmune thyroid conditions like Hashimoto’s. Many clients with burnout are misdiagnosed with “normal” thyroid function when deeper testing reveals a different story. We get the full picture.

Image by gĂĽnter from Pixabay

🧬 DUTCH Test (Dried Urine Test for Comprehensive Hormones)

alcohol, red wine

A 24-Hour Hormone Snapshot: Cortisol, Sex Hormones, and Melatonin

The DUTCH test is the gold standard for hormone testing in functional medicine. It tracks hormone rhythms over a full day and shows how your body is metabolising them.

🔍 What it reveals:

  • Cortisol and cortisone patterns (stress response)

  • DHEA (anti-aging, anti-inflammatory hormone)

  • Estrogen, progesterone, testosterone levels

  • Melatonin (sleep-wake cycle)

  • Metabolite pathways (e.g., estrogen detoxification)

đź’ˇ Why it matters for burnout:
If you’re wired at night, tired in the morning, emotionally flat, or struggling with hormonal swings—this test shows why. It’s essential for understanding how chronic stress has disrupted your endocrine system and what needs to be rebalanced.

Image by gĂĽnter from Pixabay

❤️ CardioMetabolic Testing

alcohol, red wine

Uncover Hidden Inflammation and Energy Roadblocks

Burnout isn’t just mental—it increases your risk of cardiovascular disease, diabetes, and inflammation. This blood panel gives a detailed look at metabolic and inflammatory risk.

🔍 What we assess:

  • Fasting insulin and glucose

  • HOMA-IR (insulin resistance)

  • hs-CRP (chronic inflammation)

  • Homocysteine (cardiovascular and methylation risk)

  • Cholesterol subtypes (LDL particle size, HDL function)

  • Omega-3 and Omega-6 fatty acid ratios

đź’ˇ Why it matters for burnout:
Chronic stress elevates inflammation and blood sugar, increasing the risk of heart disease, metabolic syndrome, and brain fog. Identifying these risks early helps prevent long-term disease while improving short-term energy.

Image by gĂĽnter from Pixabay

đź’ˇ What Makes Neff Functional Medicine Different?

We don’t believe in band-aids.
We believe in understanding the “why” behind your symptoms—and empowering you to heal.

🧠 Root-Cause Thinking
🤝 Personalised Care
🩺 Integrative Tools – combining science, supplements, and lifestyle strategies
đź’š Compassion-First Approach

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